Joint dependent concentrations of bone alkaline phosphatase in serum and synovial fluids of horses with osteochondral injury: an analytical and clinical validation.

@article{Trumble2008JointDC,
  title={Joint dependent concentrations of bone alkaline phosphatase in serum and synovial fluids of horses with osteochondral injury: an analytical and clinical validation.},
  author={Troy N Trumble and Murray P. Brown and Kelly A. Merritt and R. Clark Billinghurst},
  journal={Osteoarthritis and cartilage},
  year={2008},
  volume={16 7},
  pages={779-86}
}
OBJECTIVES Validate use of a commercially available immunoassay for measurement of bone alkaline phosphatase (BAP) in equine serum and synovial fluid (SF), and investigate the effects of osteochondral (OC) injury in horses on BAP concentrations in serum and SF. METHODS SF was collected from 37 joints of 34 Thoroughbred (TB) racehorses undergoing arthroscopic surgery for the removal of OC fragments from either the carpal joints (n=18) or the metacarpo-/metatarsophalangeal (MP) joints (n=19… CONTINUE READING