Joint Assessment of Structural, Perfusion, and Diffusion MRI in Alzheimer's Disease and Frontotemporal Dementia

@article{Zhang2011JointAO,
  title={Joint Assessment of Structural, Perfusion, and Diffusion MRI in Alzheimer's Disease and Frontotemporal Dementia},
  author={Yu Zhang and Norbert Schuff and Christopher R. K. Ching and Duygu Tosun and Wang Zhan and Marzieh Nezamzadeh and Howard J. Rosen and Joel H. Kramer and Maria Luisa Gorno-Tempini and Bruce L. Miller and Michael W Weiner},
  journal={International Journal of Alzheimer's Disease},
  year={2011},
  volume={2011}
}
Most MRI studies of Alzheimer's disease (AD) and frontotemporal dementia (FTD) have assessed structural, perfusion and diffusion abnormalities separately while ignoring the relationships across imaging modalities. This paper aimed to assess brain gray (GM) and white matter (WM) abnormalities jointly to elucidate differences in abnormal MRI patterns between the diseases. Twenty AD, 20 FTD patients, and 21 healthy control subjects were imaged using a 4 Tesla MRI. GM loss and GM hypoperfusion were… 
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    Journal of magnetic resonance imaging : JMRI
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