Jerarca: Efficient Analysis of Complex Networks Using Hierarchical Clustering

  title={Jerarca: Efficient Analysis of Complex Networks Using Hierarchical Clustering},
  author={Rodrigo Aldecoa and Ignacio Mar{\'i}n},
  booktitle={PloS one},
BACKGROUND How to extract useful information from complex biological networks is a major goal in many fields, especially in genomics and proteomics. We have shown in several works that iterative hierarchical clustering, as implemented in the UVCluster program, is a powerful tool to analyze many of those networks. However, the amount of computation time required to perform UVCluster analyses imposed significant limitations to its use. METHODOLOGY/PRINCIPAL FINDINGS We describe the suite… CONTINUE READING
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