Abstract

Telomeres maintain the integrity of linear chromosomes by preventing the unsolicited recruitment of DNA repair machineries to chromosome ends (de Lange, 2009; Dehé and Cooper, 2010; Jain and Cooper, 2010) and engaging telomerase to solve the end replication problem (Greider and Blackburn, 1985; Artandi and Cooper, 2009). At a distinct site on the chromosome… (More)

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