Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism.

@article{Kalia2013JapaneseEV,
  title={Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism.},
  author={Manjula Kalia and Renu Khasa and M. D. Sharma and Minu Nain and Sudhanshu Vrati},
  journal={Journal of virology},
  year={2013},
  volume={87 1},
  pages={148-62}
}
Japanese encephalitis virus (JEV) is a mosquito-borne pathogenic flavivirus responsible for acute viral encephalitis in humans. The cellular entry of JEV is poorly characterized in terms of molecular requirements and pathways. Here we present a systematic study of the internalization mechanism of JEV in fibroblasts and neuroblastoma cells. To verify the roles of distinct pathways of cell entry, we used fluorescently labeled virus particles, a combination of pharmacological inhibitors, RNA… CONTINUE READING
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