Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition

@article{Groner2017JakSS,
  title={Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition},
  author={Bernd Groner and Viktoria von Manstein},
  journal={Molecular and Cellular Endocrinology},
  year={2017},
  volume={451},
  pages={1-14}
}

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SP2509, an inhibitor of LSD1, exerts potential antitumor effects by targeting the JAK/STAT3 signaling.

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Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives

The possibilities to target JAK–STAT by focusing on its natural inhibitors as the suppressor of cytokine signaling (SOCS) proteins are reviewed.
...

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