Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.

Abstract

The Wnt and Notch signalling pathways regulate hair follicle maintenance, but how they intersect is unknown. We show that Notch signalling is active in the hair follicle pre-cortex, a region of high Wnt activity, where commitment to hair lineages occurs. Deletion of jagged 1 (Jag1) results in inhibition of the hair growth cycle and conversion of hair… (More)

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@article{Estrach2006Jagged1I, title={Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.}, author={Soline Estrach and Carrie A Ambler and Cristina Lo Celso and Katsuto Hozumi and Fiona M Watt}, journal={Development}, year={2006}, volume={133 22}, pages={4427-38} }