Jack bean (Canavalia ensiformis) urease induces eicosanoid-modulated hemocyte aggregation in the Chagas' disease vector Rhodnius prolixus.

@article{Defferrari2014JackB,
  title={Jack bean (Canavalia ensiformis) urease induces eicosanoid-modulated hemocyte aggregation in the Chagas' disease vector Rhodnius prolixus.},
  author={Marina S. Defferrari and Rosa E A da Silva and Ian Orchard and C{\'e}lia Regina Carlini},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2014},
  volume={82},
  pages={18-25}
}
Ureases are multifunctional proteins that display biological activities independently of their enzymatic function, such as induction of exocytosis and insecticidal effects. Rhodnius prolixus, a major vector of Chagas' disease, is a model for studies on the entomotoxicity of jack bean urease (JBU). We have previously shown that JBU induces the production of eicosanoids in isolated tissues of R. prolixus. In insects, the immune response comprises cellular and humoral reactions, and is centrally… CONTINUE READING