Jacaranone analogs from Senecio scandens.

  title={Jacaranone analogs from Senecio scandens.},
  author={Xiao-yan Tian and Yinghong Wang and Qiaofen Yang and Shishan Yu and Wei-shuo Fang},
  journal={Journal of Asian natural products research},
  volume={11 1},
Bioassay-guided fractionation of the ethanolic extract of Senecio scandens led to the isolation of four new compounds 4, 5, 7, and 8, along with four known jacaranone analogs (1, 2, 3, 6). Their structures were elucidated on the basis of spectral and chemical evidence. Compound 7 was obtained as a tautomeric mixture of alpha/beta-epimer. The cytotoxic activities of these compounds were evaluated. Among these, compounds 5 and 8 showed potent cytotoxicities. The benzoquinone derivative… CONTINUE READING

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