JUVENILE DERMATITIS HERPETIFORMIS IN THE LIGHT OF IMMUNOFLUORESCENCE STUDIES

@article{Jablonska1971JUVENILEDH,
  title={JUVENILE DERMATITIS HERPETIFORMIS IN THE LIGHT OF IMMUNOFLUORESCENCE STUDIES},
  author={Stephania Jablonska and Tadeusz P. Chorzelski and E. H. Beutner and Maria Błaszczyk},
  journal={British Journal of Dermatology},
  year={1971},
  volume={85}
}
Summary.— Eight cases of juvenile dermatitis herpetiformis (JDH) were investigated by direct and indirect IF methods with anti‐IgG and anti‐IgA conjugates. 
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38 Citations

Juvenile dermatitis herpetiformis: an immunoelectron microscopic study
Three children with persistent maculopapular and urticarial lesions and vesicles at the predilection sites of dermatitis herpetiformis (DH) were shown to exhibit typical granular, papillary IgA and…
Chronic nonhereditary blistering disease in children.
TLDR
Immunofluorescence has been valuable as a diagnostic aid in clarifying the relationship of dermatitis herpetiformis and bullous pemphigoid to benign chronic bullous dermatosis of childhood, which appears to be a distinct and separate entity.
BULLOUS PEMPHIGOID IN CHILDHOOD: REPORT OF THREE CASES AND A REVIEW OF LITERATURE
TLDR
Three proven cases of bullous pemphigoid in childhood which responded to dapsone are reported, indicating that the condition is a distinctive clinical entity and entirely different from dermatitis herpetiformis and benign chronic bullous dermatosis of childhood.
Juvenile dermatitis herpetiformis and chronic acquired bullous disease in children
TLDR
Eight children with chronic acquired bullous disease were studied by direct immunofluorescence and multiple jejunal biopsies were examined as well as tissue antigens (HLA‐andthcDRw3 B cell allo‐antigen) to differentiate more clearly between the different chronic acquiredBullous diseases seen in childhood.
Chronic bullous dermatosis of childhood. Linear iga bullous dermatosis.
TLDR
A 21/2-year-old boy with large, tense bullae on the groin, buttocks, legs and abdomen has had no recurrence of the disease and negative immunofluorescence study results during two years of follow-up.
Chronic bullous disease of childhood in three patients of Polynesian extraction
TLDR
Three cases of chronic bullous disease of childhood are reported who presented within I year to the Dermatology Department, Auckland Public Hospital, New Zealand.
Juvenile dermatitis herpetiformis versus "benign chronic bullous dermatosis of childhood." Are these immunologic diseases?
TLDR
Seven cases of juvenile dermatitis herpetiformis have been investigated and the question arises whether any immunologically negative cases of "benign chronic bullous dermatosis of childhood" actually exist.
IgA linear dermatosis of childhood (chronic Bullous disease of childhood)
Of twenty‐seven cases of subepidermal blistering disease of children twelve corresponded clinically, histologically and immunologically to dermatitis herpetiforms of adults, six to bullous…
Benign chronic bullous dermatosis of childhood. Linear IgA and C3 deposition on the basement membrane.
TLDR
This work reports the first case known to us in which a linear bank of IgA (but no lgG or lgM) and complement was found at the epidermal basal lamina as demonstrated by immunofluorescence studies.
Bullous disease of childhood.
Bullous disease of childhood (BDC) is a persistent or recurrent blistering skin disease characterized by large, tense bullae in a generalized distribution, but with a predilection for the scalp,…
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References

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TLDR
Evidence supports the concept that this entity is probably a bullous variant of dermatitis herpetiformis, which occurred in an infant.
GRANULAR DEPOSITS OF IMMUNOGLOBULINS IN THE SKIN OF PATIENTS WITH DERMATITIS HERPETIFORMIS. AN IMMUNOFLUORESCENT STUDY
SUMMARY.— Direct immunofluorescent technique applied to skin sections revealed the occurrence of granular deposits of immunoglobulins in the basement membrane zone of the uninvolved skin from 10 of…
IMMUNO‐HISTOPATHOLOGY OF THE SKIN IN PEMPHIGOID
SUMMARY.— The in vivo direct immunofluorescent (DIF) staining patterns of the skin surrounding the lesions of 5 patients suffering from pemphigoid are reported.
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The initiation and course of a chronic blistering disease and immunologic changes characteristic of bullous pemphigoid in an 11-year-old boy suggested that an allergic reaction to one or more drugs…
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TLDR
Evaluation of IF studies, together with the clinical picture, histology, and response to sulfapyridine, points to the importance of immunopathology in the differentiation between dh and bp.
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TLDR
Indirect immunofluorescent staining revealed that the sera of six patients with active childhood bullous dermatitis herpetiformis were negative for basement-membrane zone or "pemphigoid" antibodies, and this disease appears to be immunologically distinct from bullous pemphIGoid as it occurs in the adult.
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DERMATITIS HERPETIFORMIS IN CHILDREN
  • C. Berlin
  • Medicine
    The British journal of dermatology
  • 1952
TLDR
The accepted view of the dermatologist, therefore, is that dermatitis herpetiformis is rare in childhood.
Factors contributing to occasional failures in demonstration of pemphigus antibodies by the immunofluorescence test.
TLDR
In vivo binding of IgG to the intercellular areas can, however, be demonstrated in sections of biopsies of lesions even when the indirect staining fails to reveal the presence of pemphigus antibodies.
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