JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.

@article{Lisanti2014JNK1SS,
  title={JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.},
  author={Michael Phillip Lisanti and Aristotelis Tsirigos and Stephanos Pavlides and Kimberley Jayne Reeves and Maria Peiris-Pag{\'e}s and Amy L. Chadwick and Rosa S{\'a}nchez-Alvarez and Rebecca Lamb and Anthony Howell and Ubaldo e. Martinez-outschoorn and Federica Sotgia},
  journal={Cell cycle},
  year={2014},
  volume={13 4},
  pages={580-99}
}
Mammography is an important screening modality for the early detection of DCIS and breast cancer lesions. More specifically, high mammographic density is associated with an increased risk of breast cancer. However, the biological processes underlying this phenomenon remain largely unknown. Here, we re-interrogated genome-wide transcriptional profiling data obtained from low-density (LD) mammary fibroblasts (n = 6 patients) and high-density (HD) mammary fibroblasts (n = 7 patients) derived from… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 7 times over the past 90 days. VIEW TWEETS
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…