JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells

Abstract

Aim:Many studies reveal an association between the acquired chemoresistant phenotype of cancer cells and tumor-initiating cell-like properties. The aim of this study was to determine the impact of c-Jun N-terminal kinase (JNK) on the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells.Methods:Two well-established human… (More)
DOI: 10.1038/aps.2015.58

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