JNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposure.

Abstract

Environmental exposure to arsenic, especially the trivalent inorganic form (As(3+)), has been linked to human cancers in addition to a number of other diseases including skin lesions, cardiovascular disorders, neuropathy, and internal organ injury. In the present study, we describe a novel signaling axis of the c-Jun NH2 kinase (JNK) and signal transducer… (More)
DOI: 10.1093/toxsci/kfs199

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.