JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila.

@article{MartnBlanco2000JNKAD,
  title={JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila.},
  author={Enrique Mart{\'i}n-Blanco and Jos{\'e} Carlos Pastor-Pareja and Antonio Garc{\'i}a-Bellido},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 14},
  pages={7888-93}
}
One of the fundamental events in metamorphosis in insects is the replacement of larval tissues by imaginal tissues. Shortly after pupariation the imaginal discs evaginate to assume their positions at the surface of the prepupal animal. This is a very precise process that is only beginning to be understood. In Drosophila, during embryonic dorsal closure, the epithelial cells push the amnioserosa cells, which contract and eventually invaginate in the body cavity. In contrast, we find that during… CONTINUE READING