JNK Signalling Controls Remodelling of the Segment Boundary through Cell Reprogramming during Drosophila Morphogenesis

@inproceedings{Gettings2010JNKSC,
  title={JNK Signalling Controls Remodelling of the Segment Boundary through Cell Reprogramming during Drosophila Morphogenesis},
  author={Melanie Gettings and Fanny Serman and Rapha{\"e}l Rousset and Patrizia Bagnerini and Luis Fernando de Almeida and St{\'e}phane Noselli},
  booktitle={PLoS biology},
  year={2010}
}
Segments are fundamental units in animal development which are made of distinct cell lineages separated by boundaries. Although boundaries show limited plasticity during their formation for sharpening, cell lineages make compartments that become tightly restricted as development goes on. Here, we characterize a unique case of breaking of the segment boundary in late drosophila embryos. During dorsal closure, specific cells from anterior compartments cross the segment boundary and enter the… CONTINUE READING

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