JEvTrace: refinement and variations of the evolutionary trace in JAVA

@article{Joachimiak2002JEvTraceRA,
  title={JEvTrace: refinement and variations of the evolutionary trace in JAVA},
  author={Marcin P. Joachimiak and Fred E. Cohen},
  journal={Genome Biology},
  year={2002},
  volume={3},
  pages={research0077.1 - research0077.12}
}
Details of functional speciation within gene families can be difficult to identify using standard multiple sequence alignment (MSA) methods. The evolutionary trace (ET) was developed as a visualization tool to combine MSA, phylogenetic and structural data for identification of functional sites in proteins. The method has been successful in extracting evolutionary details of functional surfaces in a number of biological systems and modifications of the method are useful in creating hypotheses… CONTINUE READING
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