JC9813-A putative novel human papillomavirus identified by PCR-DS.


Papillomaviruses consist of more than 130 viral types described so far. Most of them are human papillomaviruses (HPV) of supergroup A, demonstrating ano-genital tropism and characterized as etiological agents for benign and malignant cervical lesions in women. A PCR-direct sequencing (PCR-DS) approach with P-33 labeled dideoxynucleotides was used to detect and type human papillomaviruses in cervical biopsies. One novel sequence was identified in a LSIL (low-grade squamous intraepithelial lesions) specimen from an HIV-positive English Canadian patient. The structure of the viral gene L1 was determined, yielding a putative novel HPV type of supergroup A (clade A8) named JC9813.

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@article{FeoliFonseca1998JC9813APN, title={JC9813-A putative novel human papillomavirus identified by PCR-DS.}, author={J-C Feoli-Fonseca and Luc Laurier Oligny and Martin Filion and Pascale Simard and Pierre A. Russo and Wagner V. Yotov}, journal={Biochemical and biophysical research communications}, year={1998}, volume={250 1}, pages={63-7} }