JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7

Abstract

JC virus (JCV) is a human polyomavirus that infects the central nervous system (CNS) of immunocompromised patients. JCV granule cell neuronopathy (JCV-GCN) is caused by infection of cerebellar granule cells, causing ataxia. A 77-year-old man with iatrogenic lymphopenia presented with severe ataxia and was diagnosed with JCV-GCN. His ataxia and cerebrospinal… (More)
DOI: 10.1007/s13365-016-0465-0

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