JC virus VP1 loop-specific polymorphisms are associated with favorable prognosis for progressive multifocal leukoencephalopathy

@article{Delbue2011JCVV,
  title={JC virus VP1 loop-specific polymorphisms are associated with favorable prognosis for progressive multifocal leukoencephalopathy},
  author={S. Delbue and E. Branchetti and S. Bertolacci and E. Tavazzi and E. Marchioni and R. Maserati and Giulia Minnucci and S. Tremolada and G. Vago and P. Ferrante},
  journal={Journal of NeuroVirology},
  year={2011},
  volume={15},
  pages={51-56}
}
  • S. Delbue, E. Branchetti, +7 authors P. Ferrante
  • Published 2011
  • Biology, Medicine
  • Journal of NeuroVirology
  • JC virus (JCV) is a human polyomavirus that causes progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease that mainly affects immunocompromised subjects. Since its discovery, PML has been considered a rapidly progressing fatal disease; however, amino acid substitutions in the capsid viral protein have recently been tentatively associated with changes in PML clinical course. In order to provide more insight to PML pathogenesis and identify potential prognostic markers… CONTINUE READING
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