JAMM: a peak finder for joint analysis of NGS replicates

  title={JAMM: a peak finder for joint analysis of NGS replicates},
  author={Mahmoud M. Ibrahim and Scott A. Lacadie and Uwe Ohler},
  volume={31 1},
MOTIVATION Although peak finding in next-generation sequencing (NGS) datasets has been addressed extensively, there is no consensus on how to analyze and process biological replicates. Furthermore, most peak finders do not focus on accurate determination of enrichment site widths and are not widely applicable to different types of datasets. RESULTS We developed JAMM (Joint Analysis of NGS replicates via Mixture Model clustering): a peak finder that can integrate information from biological… CONTINUE READING
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