JAK2-V617F activates β1-integrin-mediated adhesion of granulocytes to vascular cell adhesion molecule 1


function. This assay confirmed an absence of DNA-binding affinity to the DNA sequences derived from human PC-HC in the mutated IKAROS protein (Supplementary Figure S3b). On the basis of previous analyses on specific single amino acid substitutions in IKAROS, we are aware that only six amino acid regions (154, 159, 162, 180, 184 and 188) within the second or… (More)
DOI: 10.1038/leu.2017.26


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