JAK2/STAT3 directs cardiomyogenesis within murine embryonic stem cells in vitro.

Abstract

The heart is the first organ to form during development; however, little is known about the mechanisms that control the initial stages of cardiac differentiation. To investigate this process, we used a protein kinase expression screen, in which nonbeating embryonic stem (ES) cells were compared with beating ES cell-derived cardiomyocytes. We found that JAK2… (More)

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@article{Foshay2005JAK2STAT3DC, title={JAK2/STAT3 directs cardiomyogenesis within murine embryonic stem cells in vitro.}, author={Kara M Foshay and Gisella Rodriguez and Bonnie Hoel and Jonathon Narayan and G Ian Gallicano}, journal={Stem cells}, year={2005}, volume={23 4}, pages={530-43} }