J.J. Bonica Lecture--2000: Physiology, pathophysiology, and pharmacology of visceral pain.

@article{Gebhart2000JJBL,
  title={J.J. Bonica Lecture--2000: Physiology, pathophysiology, and pharmacology of visceral pain.},
  author={Gerald F. Gebhart},
  journal={Regional anesthesia and pain medicine},
  year={2000},
  volume={25 6},
  pages={632-8}
}
BACKGROUND AND OBJECTIVES The principal objective of this report is to review recent experimental advances in our understanding of the physiology and pathophysiology of visceral pain and to describe results of studies of opioid modulation of visceral nociception. METHODS Results are drawn from electrophysiological studies of single pelvic nerve afferent fibers innervating the descending colon in the rat. RESULTS The important findings include the following: identification of a subset of… CONTINUE READING

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