J.Hard Tissue Biology.15(1):27- 33,2006 Effects of Immobilized rhBMP-2/atelocollagen in vivo and in vitro


The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to induce ectopic bone formation requires a carrier. Atelocollagen, a biomaterial with a porous structure, excellent operational features and biocompatibility, is known to be an effective carrier for rhBMP-2. However, conventionally used lyophilized rhBMP-2/atelocollagen mixture does not… (More)


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