J. Clifford Richardson and 50 years of progressive supranuclear palsy.

@article{Williams2008JCR,
  title={J. Clifford Richardson and 50 years of progressive supranuclear palsy.},
  author={David R. Williams and A. J. Lees and John R. Wherrett and John Charles Steele},
  journal={Neurology},
  year={2008},
  volume={70 7},
  pages={566-73}
}
OBJECTIVE To trace the historical events leading to Richardson's clinical description of progressive supranuclear palsy (PSP) in the context of subsequent observations of its clinical heterogeneity and pathologic overlap with other tauopathies. BACKGROUND Fifty years ago, Canadian neurologist J. Clifford Richardson identified patients in Toronto with a syndrome of supranuclear vertical gaze palsy, pseudobulbar palsy, axial rigidity-in-extension, and cognitive impairment. In his seminal… CONTINUE READING
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