The authors detail the life and career of Dr. J. Lawrence Pool, as well as his significant contributions to the field of cerebrovascular neurosurgery. The discipline of cerebrovascular neurosurgery is a young and dynamic field, which underwent rapid and substantial growth during the middle of the twentieth century. As the chairman of the Department of Neurological Surgery at the Neurological Institute of New York, Dr. J. Lawrence Pool was instrumental in the development of new techniques and devices that would ultimately result in decreased mortality rates and improved results from complex cerebrovascular procedures. Passion, ingenuity, and a pioneering spirit fueled Dr. Pool, whose introduction of the operating microscope and use of temporary clip occlusion during aneurysm repair revolutionized the field of cerebrovascular neurosurgery.