Ixodid tick salivary gland products target host wound healing growth factors.


For successful blood-feeding, ticks must confront the host immune system comprising many cells and signaling molecules, mainly cytokines and growth factors. These factors bind to specific receptors on the cell membranes, thereby initiating a signaling cascade that leads to distinct cellular activities. Ticks are able to manipulate host immune responses via… (More)
DOI: 10.1016/j.ijpara.2010.09.005