Ixodes tick saliva suppresses the keratinocyte cytokine response to TLR2/TLR3 ligands during early exposure to Lyme borreliosis.

@article{Bernard2016IxodesTS,
  title={Ixodes tick saliva suppresses the keratinocyte cytokine response to TLR2/TLR3 ligands during early exposure to Lyme borreliosis.},
  author={Quentin Bernard and Richard L Gallo and Beno{\^i}t Jaulhac and Teruaki Nakatsuji and Benjamin J. Luft and Xiahoua Yang and Nathalie M Boulanger},
  journal={Experimental dermatology},
  year={2016},
  volume={25 1},
  pages={26-31}
}
Ixodes hard tick induces skin injury by its sophisticated biting process. Its saliva plays a key role to enable an efficient blood meal that lasts for several days. We hypothesized that this feeding process may also be exploited by pathogens to facilitate their transmission, especially in the context of arthropod-borne diseases. To test this, we used Lyme borreliosis as a model. This bacterial infection is caused by Borrelia burgdorferi sensu lato transmitted by Ixodes. We co-incubated Borrelia… CONTINUE READING
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