Item, context and relational episodic encoding in humans

@article{Davachi2006ItemCA,
  title={Item, context and relational episodic encoding in humans},
  author={Lila Davachi},
  journal={Current Opinion in Neurobiology},
  year={2006},
  volume={16},
  pages={693-700}
}
  • L. Davachi
  • Published 1 December 2006
  • Psychology, Biology
  • Current Opinion in Neurobiology

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References

SHOWING 1-10 OF 72 REFERENCES
Multiple routes to memory: Distinct medial temporal lobe processes build item and source memories
TLDR
This work used event-related functional MRI to examine the relation between activation in distinct medial temporal lobe subregions during memory formation and the ability to later recognize an item as previously encountered and later recollect specific contextual details about the prior encounter.
Hippocampal contribution to the novel use of relational information in declarative memory
TLDR
Selective hippocampal activation in humans during recognition of pairs of items whose relationship was not explicitly learned but could be mediated through an overlapping relation with an explicitly learned common item suggests a specific role for the human hippocampus in the novel expression of declarative memories.
Common pathway in the medial temporal lobe for storage and recovery of words as revealed by event‐related functional MRI
TLDR
The results suggest that the parahipp hippocampal/hippocampal region is involved in the formation and subsequent reactivation of memory traces, whereas the activity observed in the entorhinal cortex may reflect elementary memory processes related to novelty detection.
Working Memory for Conjunctions Relies on the Medial Temporal Lobe
TLDR
The hypothesis that the medial temporal lobes are important for relational memory even over short delays is tested and it is proposed that the hippocampus is critically involved in memory for conjunctions at both short and long delays.
Medial temporal lobe activation during encoding and retrieval of novel face-name pairs
TLDR
Functional magnetic resonance imaging is used to measure brain activity during learning and later recognition testing of novel face‐name pairs and shows that there is greater activity for successful encoding of associative information than for non‐associative information in the right hippocampal region, as well as in the left amygdala and right parahippocampal cortex.
Encoding activity in anterior medial temporal lobe supports subsequent associative recognition
Memory deficits for implicit contextual information in amnesic subjects with hippocampal damage
TLDR
It is demonstrated that the human medial temporal memory system is important for learning contextual information, which requires the binding of multiple cues, which could be classified as implicit.
...
...