Itch promotes the neddylation of JunB and regulates JunB-dependent transcription.

Abstract

Protein neddylation is essential for the viability of most organisms and is widely involved in the regulation of immunity, DNA damage and repair, cell signaling and cell cycle. Unlike RING-type neddylation ligases, HECT-type neddylation ligase remains less defined. Here, we show that Itch is a novel HECT-type neddylation E3 ligase and we identify JunB as a… (More)
DOI: 10.1016/j.cellsig.2016.05.016

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Cite this paper

@article{Li2016ItchPT, title={Itch promotes the neddylation of JunB and regulates JunB-dependent transcription.}, author={Haiwen Li and Heng Zhu and Yang Liu and Fuchu He and Ping Xie and Lingqiang Zhang}, journal={Cellular signalling}, year={2016}, volume={28 9}, pages={1186-95} }