Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord

@inproceedings{Goswami2014ItchassociatedPR,
  title={Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord},
  author={Samridhi C Goswami and Danielle Thierry-Mieg and Jean Thierry-Mieg and Santosh Kumar Mishra and Mark A Hoon and Andrew J Mannes and Michael J Iadarola},
  booktitle={Molecular pain},
  year={2014}
}
BACKGROUND Three neuropeptides, gastrin releasing peptide (GRP), natriuritic precursor peptide B (NPPB), and neuromedin B (NMB) have been proposed to play roles in itch sensation. However, the tissues in which these peptides are expressed and their positions in the itch circuit has recently become the subject of debate. Here we used next-gen RNA-Seq to examine the expression of transcripts coding for GRP, NPPB, NMB, and other peptides in DRG, trigeminal ganglion, and the spinal cord as well as… CONTINUE READING
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