Itch and brain

@article{Mochizuki2015ItchAB,
  title={Itch and brain},
  author={Hideki Mochizuki and Ryusuke Kakigi},
  journal={The Journal of Dermatology},
  year={2015},
  volume={42}
}
Itch is an unpleasant somatic sensation that evokes the urge to scratch. Chronic itch is a severe problem that diminishes quality of life. There are many patients suffering from chronic itch across the world. The brain is the final terminal to receive itch‐related signals from the body and plays an important role in perceiving the itch sensation. Thus, to understand the cerebral mechanism of itch perception and how this mechanism differs between healthy subjects and chronic itch patients is… Expand
8 Citations
Differential roles of prelimbic and anterior cingulate cortical region in the modulation of histaminergic and non-histaminergic itch
TLDR
This study provided direct evidence of Prl involvement in itch modulation and revealed the differential roles of caudal ACC and Prl in regulating histaminergic and non-histaminergic itch. Expand
Assessment of the impact of sex in intensity, skin flares and central processing of histaminergic itch—A pilot study
Itch is the commonest skin‐related symptom, and sex differences are increasingly recognised as important determinants in stratified medicine, but only little is known about sex differences in itch.Expand
Increased grey matter volume and associated resting-state functional connectivity in chronic spontaneous urticaria: A structural and functional MRI study.
TLDR
The findings indicate that patients suffering from chronic itching conditions, such as CSU, are likely to demonstrate altered GM volume in some brain regions associated with cognitive function. Expand
Functional magnetic resonance imaging in dermatology: The skin, the brain and the invisible
TLDR
A review looks back to the beginnings of functional neuroimaging in dermatology, summarises the currently available dermatology‐related fMRI studies and discusses the potential future role of fMRI as a stratifying tool in clinical dermatology and in the development of novel therapies. Expand
Gender Differences in the Association of Brain Gray Matter and Pain-Related Psychosocial Characteristics.
TLDR
Gray matter morphology relates differently to psychosocial characteristics in women and men and provides ideas for further research to investigate if targeting perceived negative consequences of the illness, perceived emotional representations, perceived chronicity, and pain catastrophizing in women, and perceived personal control of the illnesses and kinesiophobia in men, could contribute to the normalization of brain alterations in people with nonspecific chronic spinal pain. Expand
Itch in Atopic Dermatitis.
TLDR
Exploring itch pathways and mechanisms may lead to novel therapeutic approaches for atopic itch. Expand
Skin-Picking-Syndrom
TLDR
In the new DSM-V, skin-picking disorder has been included in the diagnostic system as an independent disorder and describes the self-injury of the skin by picking or scratching with an underlying emotional disorder. Expand
Use of a mechanical brush by dairy cows with chorioptic mange
TLDR
Assessment of changes in dairy cow motivation to use a brush in relation to signs of mange, and before and after the application of an anti-parasitic drug, indicates that brush use in mange-affected cows decreases after initial usage, and that regardless of the severity of mane, access to a grooming device is a valuable resource for dairy cows. Expand

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TLDR
This study is the first to identify networks activated by scratching-induced pleasantness, and provides important information on the cerebral mechanisms underlying why scratching itchy skin evokes pleasurable feelings that reinforce scratching behaviors. Expand
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TLDR
FMRI time series analysis demonstrates that the difference in the sensitivity of PCC, the posterior insula and the thalamus between itching and pain would be responsible for the perceptual difference between these sensations. Expand
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TLDR
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TLDR
Findings indicate that brain regions associated with imagery of itch are the same as those involved in imagery of pain, but their functional networks differ, which may explain why motor responses to itch are more socially contagious than those related to pain. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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