It is a complex issue: emerging connections between epigenetic regulators in drug addiction

  title={It is a complex issue: emerging connections between epigenetic regulators in drug addiction},
  author={Ethan M. Anderson and Rachel D. Penrod and Sarah M. Barry and Brandon W Hughes and Makoto Taniguchi and Christopher W. Cowan},
  journal={European Journal of Neuroscience},
Drug use leads to addiction in some individuals, but the underlying brain mechanisms that control the transition from casual drug use to an intractable substance use disorder (SUD) are not well understood. Gene x environment interactions such as the frequency of drug use and the type of substance used likely to promote maladaptive plastic changes in brain regions that are critical for controlling addiction‐related behavior. Epigenetics encompasses a broad spectrum of mechanisms important for… 
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Neuroepigenetics and addiction.
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