It Takes a Tissue to Make a Tumor: Epigenetics, Cancer and the Microenvironment


How do normal tissues limit the development of cancer? This review discusses the evidence that normal cells effectively restrict malignant behavior, and that such tissue forces must be subjugated to establish a tumor. The action of ionizing radiation will be specifically discussed regarding the disruption of the microenvironment that promotes the transition… (More)
DOI: 10.1023/A:1011317009329


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