Issues relating to the use of BCG in immunization programmes A discussion document
@inproceedings{Fine1999IssuesRT, title={Issues relating to the use of BCG in immunization programmes A discussion document}, author={Paul E M Fine and Ilona A Carneiro and Julie B. Milstien and C. John Clements}, year={1999} }
1 Infectious Disease Epidemiology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England. 2 Scientist, Department of Vaccines and Biologicals, Health Technology and Pharmaceuticals, World Health Organization, 1211 Geneva 27, Switzerland. 3 Medical Officer, Department of Vaccines and Biologicals, Health Technology and Pharmaceuticals,World Health Organization, 1211 Geneva 27, Switzerland.
165 Citations
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There is no evidence that when administered to newborns different preparations of BCG vaccine exhibit different efficacies, but other factors, including dose, administration technique, and recipient characteristics are also important in determining vaccine-associated reactions.
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Findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic, and suggest that smallpox immunization had no effect.
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Although the studies had too many methodological flaws to be combined in a quantitative meta-analysis, they suggest that vaccination with BCG is effective in reducing the incidence of tuberculosis among health care workers.
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