Issues relating to confounding and meta-analysis when including non-randomized studies in systematic reviews on the effects of interventions.

Abstract

BACKGROUND Confounding caused by selection bias is often a key difference between non-randomized studies (NRS) and randomized controlled trials (RCTs) of interventions. KEY METHODOLOGICAL ISSUES In this third paper of the series, we consider issues relating to the inclusion of NRS in systematic reviews on the effects of interventions. We discuss whether… (More)
DOI: 10.1002/jrsm.1064

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