Issues related to subgroup analysis in clinical trials.

@article{Cui2002IssuesRT,
  title={Issues related to subgroup analysis in clinical trials.},
  author={Lu Cui and H. M. James Hung and Sue Jane Wang and Y I Tsong},
  journal={Journal of biopharmaceutical statistics},
  year={2002},
  volume={12 3},
  pages={347-58}
}
Interpretation of subgroup findings is a difficult task. The attempt of this article is to clarify confusions on subgroup analysis and to give some practical suggestions on how to avoid mistakes in interpreting subgroup outcome. We believe that the correct interpretation of subgroup findings is closely related to the intrinsic statistical property and validity of the subgroup analysis. A systematic discussion on subgroup analysis from a statistical point of view will be helpful to clinical… CONTINUE READING

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