Issues in evolutionary medicine

@article{Stearns2005IssuesIE,
  title={Issues in evolutionary medicine},
  author={S. Stearns},
  journal={American Journal of Human Biology},
  year={2005},
  volume={17}
}
  • S. Stearns
  • Published 2005
  • Biology, Medicine
  • American Journal of Human Biology
  • This paper illustrates the utility of applying evolutionary thought to medical issues with three examples: selection arenas, aging, and tradeoffs. First, the human female reproductive tract functions as a selection arena at two levels: in the ovaries, where atresia reduces the number of oocytes by more than 99.99% before any are ovulated, and in the uterus, where early embryos homozygous for immune genes are spontaneously aborted. These selective filters early in life have implications both for… CONTINUE READING
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    References

    SHOWING 1-10 OF 25 REFERENCES
    Evolution in Health and Disease: Work in Progress
    • 87
    The bottleneck: mitochondrial imperatives in oogenesis and ovarian follicular fate
    • 227
    Optimally, mutation and the evolution of ageing
    • 532
    MHC-dependent mate preferences in humans
    • 848
    • PDF
    THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCE.
    • 964
    Genetics of Aging in Drosophila
    • 14