Issues and challenges with integrating patient-reported outcomes in clinical trials supported by the National Cancer Institute-sponsored clinical trials networks.

@article{Bruner2007IssuesAC,
  title={Issues and challenges with integrating patient-reported outcomes in clinical trials supported by the National Cancer Institute-sponsored clinical trials networks.},
  author={Deborah W. Bruner and Charlene J Bryan and Neil A Aaronson and Christopher Craig Blackmore and Michael Brundage and David Cella and Patricia A. Ganz and Carolyn Gotay and Pamela S. Hinds and A. Borris Kornblith and Benjamin Movsas and Jeff A. Sloan and Lari Wenzel and Giles Whalen},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2007},
  volume={25 32},
  pages={5051-7}
}
PURPOSE The objective of this report is to provide a historical overview of and the issues and challenges inherent in the incorporation of patient-reported outcomes (PROs) into multinational cancer clinical trials in the cancer cooperative groups. METHODS An online survey of 12 cancer cooperative groups from the United States, Canada, and Europe was conducted between June and August of 2006. Each of the cooperative groups designated one respondent, who was a member of one of the PRO… CONTINUE READING

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