Ispaghula therapy in irritable bowel syndrome: Improvement in overall well‐being is related to reduction in bowel dissatisfaction

@article{Jalihal1990IspaghulaTI,
  title={Ispaghula therapy in irritable bowel syndrome: Improvement in overall well‐being is related to reduction in bowel dissatisfaction},
  author={Anand Jalihal and George Prashanth Kurian},
  journal={Journal of Gastroenterology and Hepatology},
  year={1990},
  volume={5}
}
  • A. Jalihal, G. Kurian
  • Published 1 October 1990
  • Medicine
  • Journal of Gastroenterology and Hepatology
This placebo controlled, double‐blind, cross‐over trial involving 20 patients was conducted to assess the effect of ispaghula husk on the major bowel symptoms and the whole gut transit time in irritable bowel syndrome (IBS) and to determine if changes in these parameters were related to global improvement. All 20 patients were interviewed at the end of the treatment periods and 14 patients kept concurrent daily records. Ispaghula therapy resulted in improvement in global symptoms and satisfying… 

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TLDR
Ispaghula significantly improves overall well being in patients with irritable bowel syndrome, and in those with constipation favourably affects bowel habit and transit time.

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TLDR
It is concluded that the optimum dose of ispaghula husk in irritable bowel syndrome is 20 g per day and there is some correlation between the increase in stool weight and the improvement in symptom score but the whole gut transit time remains unchanged despite alterations in stool Weight and patients' symptoms.

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