Ispaghula therapy in irritable bowel syndrome: Improvement in overall well‐being is related to reduction in bowel dissatisfaction

@article{Jalihal1990IspaghulaTI,
  title={Ispaghula therapy in irritable bowel syndrome: Improvement in overall well‐being is related to reduction in bowel dissatisfaction},
  author={Anand Jalihal and George Kurian},
  journal={Journal of Gastroenterology and Hepatology},
  year={1990},
  volume={5}
}
  • A. Jalihal, G. Kurian
  • Published 1 October 1990
  • Medicine
  • Journal of Gastroenterology and Hepatology
This placebo controlled, double‐blind, cross‐over trial involving 20 patients was conducted to assess the effect of ispaghula husk on the major bowel symptoms and the whole gut transit time in irritable bowel syndrome (IBS) and to determine if changes in these parameters were related to global improvement. All 20 patients were interviewed at the end of the treatment periods and 14 patients kept concurrent daily records. Ispaghula therapy resulted in improvement in global symptoms and satisfying… 
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[Guidelines for the treatment of irritable bowel syndrome].
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Both tricyclic antidepressants and selective serotonin reuptake inhibitors are equally effective in relieving global IBS symptoms, and have some benefits in treating abdominal pain.
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References

SHOWING 1-10 OF 20 REFERENCES
Double blind study of ispaghula in irritable bowel syndrome.
TLDR
Ispaghula significantly improves overall well being in patients with irritable bowel syndrome, and in those with constipation favourably affects bowel habit and transit time.
Optimum dosage of ispaghula husk in patients with irritable bowel syndrome: correlation of symptom relief with whole gut transit time and stool weight.
TLDR
It is concluded that the optimum dose of ispaghula husk in irritable bowel syndrome is 20 g per day and there is some correlation between the increase in stool weight and the improvement in symptom score but the whole gut transit time remains unchanged despite alterations in stool Weight and patients' symptoms.
What is the benefit of coarse wheat bran in patients with irritable bowel syndrome?
TLDR
Coarse wheat bran was no better than placebo for most symptoms in irritable bowel syndrome, although its efficacy in constipation was confirmed, and it predicted a successful outcome with bran.
Psyllium therapy in the irritable bowel syndrome. A double-blind trial.
TLDR
A major placebo effect occurs in patients with painful irritable bowel syndrome and is probably responsible for the efficacy of psyllium.
Irritable bowel syndrome: relationship of disorders in the transit of a single solid meal to symptom patterns.
TLDR
The results indicate that irritable bowel syndrome should be considered a disease of the small intestine as well as the colon.
A DOUBLE-BLIND TRIAL OF THE EFFECT OF WHEAT BRAN ON SYMPTOMS OF IRRITABLE BOWEL SYNDROME
TLDR
The results of this trial do not support the routine use of miller's bran in irritable bowel syndrome.
The effect of coarse wheat bran in the irritable bowel syndrome. A double-blind cross-over study.
TLDR
It is concluded that coarse Wheat bran used as the only treatment in IBS does not provide a sufficient effect in a 6-week period, but wheat bran seems to be justified in the treatment of constipation.
Is bran efficacious in irritable bowel syndrome? A double blind placebo controlled crossover study.
TLDR
The data suggest that in irritable bowel syndrome, especially that associated with abdominal pain, the beneficial effects of bran are due to a placebo response which is independent of an increase in stool weight.
Treatment of irritable bowel syndrome with lorazepam, hyoscine butylbromide, and ispaghula husk.
TLDR
These therapeutic results, though far from perfect, show that the types of drug commonly used to treat IBS are of some value and may be additive in their effects.
A diagnostic score for the irritable bowel syndrome. Its value in the exclusion of organic disease.
TLDR
It is concluded that a detailed history, physical examination, and basic laboratory tests are sufficient in most patients for the positive diagnosis of irritable bowel syndrome and the exclusion of any underlying organic diseases.
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