Isozyme specific changes in the expression of protein kinase C isozyme ( a-~ " ) genes in the hippocampus of rats induced by kindling epileptogenesis

The transcript levels of the protein kinase C (PKC) isoform genes during the development of a kindled epileptogenic focus, elicited by stimulation of Schaffer collateral/commissural fibres in the CA1 area of the rat hippocampus, were compared with the expression levels in control animals using a semi-quantitative in situ hybridization approach. In the… CONTINUE READING