Isozyme distribution of hexokinase, phosphofructokinase and pyruvate kinase in lymphocytes from patients with chronic lymphocytic leukemia.

@article{Kraaijenhagen1982IsozymeDO,
  title={Isozyme distribution of hexokinase, phosphofructokinase and pyruvate kinase in lymphocytes from patients with chronic lymphocytic leukemia.},
  author={Rob J. Kraaijenhagen and Gijsbert C de Gast and Marcel van der Heijden and M. Streefkerk and Frits H. J. Gmelig-Meyling and Gert Rijksen and Gerard E. J. Staal},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1982},
  volume={124 1},
  pages={91-101}
}
The enzyme activities and isozyme distribution of the three glycolytic regulator enzymes hexokinase, phosphofructokinase and pyruvate kinase were studied in lymphocytes of patients with chronic lymphocytic leukemia. Isozyme distribution patterns were determined by kinetic measurements, electrophoresis and immunoprecipitation. The CLL lymphocytes were different from normal non-T lymphocytes with respect to hexokinase residual activity in the presence of glucose-1,6-P2, pyruvate kinase residual… CONTINUE READING

Similar Papers

Loading similar papers…