Isotretinoin therapy and mood changes in adolescents with moderate to severe acne: a cohort study.
@article{Chia2005IsotretinoinTA, title={Isotretinoin therapy and mood changes in adolescents with moderate to severe acne: a cohort study.}, author={Christina Y. Chia and W. Lane and J. Chibnall and A. Allen and Elaine S. Siegfried}, journal={Archives of dermatology}, year={2005}, volume={141 5}, pages={ 557-60 } }
OBJECTIVE
To determine whether patients with moderate to severe acne who were treated with isotretinoin experienced significant increases in depressive symptoms over a 3- to 4-month period compared with patients who received conservative acne therapy.
DESIGN
Cohort study.
SETTING
Hospital-affiliated and community-based clinics in St Louis, Mo.
PARTICIPANTS
One hundred thirty-two subjects aged 12 to 19 years with moderate to severe acne.
MAIN OUTCOME MEASURES
Depressive symptoms were… CONTINUE READING
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