Isotretinoin in lacrimal gland fluid and tears.


Isotretinoin (13-cis-retinoic acid) is used in the treatment of severe cystic acne. Adverse ocular reactions, including blepharoconjunctivitis and dry eye symptoms, are frequent side effects of this drug. Our previous observation that retinol is present in tears and lacrimal gland fluid suggests that isotretinoin may also be secreted by the lacrimal gland… (More)


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@article{Rismondo1987IsotretinoinIL, title={Isotretinoin in lacrimal gland fluid and tears.}, author={Vivian Rismondo and John L. Ubels}, journal={Archives of ophthalmology}, year={1987}, volume={105 3}, pages={416-20} }