Isotretinoin for severe acne

  title={Isotretinoin for severe acne},
  author={MICHAEL A. James},
  journal={The Lancet},
  • M. James
  • Published 22 June 1996
  • Medicine
  • The Lancet
10 Citations
The effect of oral isotretinoin on visual contrast sensitivity and amount of lacrimation in patients with acne vulgaris
This study is significant in that it is the first to investigate the effects of isotretinoin on visual contrast sensitivity that is closely associated with real-world performance and needs to be supported by future studies.
Treating adult acne vulgaris: a summary of the topical and oral preparations
This article demonstrates how dermatology and aesthetic medicine combined can benefit patients with this skin condition.
Online Purchasing of Isotretinoin: E-Pharmacies Provision of Safety Information
Women of child bearing age have the option to self-purchase Isotretinoin directly from web sites that do not provide any form of risk assessment, pregnancy prevention education, or warnings of the dangers associated with taking this medication.
Can We Ensure the Safe Use of Known Human Teratogens?
The manufacturers of isotretinoin implemented a new risk-management programme, iPLEDGE™, in March 2006, that includes mandatory registration of patients, healthcare providers, pharmacies, and wholesalers and allows real-time linkage of pregnancy-test results for verification prior to the dispensing of isot retinoin.
Isotretinoin, depression and suicide: a review of the evidence.
  • P. Magin, D. Pond, Wayne Smith
  • Psychology
    The British journal of general practice : the journal of the Royal College of General Practitioners
  • 2005
While isotretinoin, used to treat acne vulgaris, has not been demonstrated to be associated with depression or suicide, the possibility of a relatively rare idiosyncratic adverse effect remains.
Can We Ensure the Safe Use of Known Human Teratogens?
Though the introduction of generic versions of isotretinoin further complicates risk management, the companies marketing isot retinoin have an opportunity to work together to demonstrate their commitment to both limit the occurrence of exposed pregnancies and conduct a meaningful evaluation of the occurrence.
The Effect of Isotretinoin on Biotinidase Activity
It is suggested that isotretinoin isomers-metabolites act in the liver, resulting in low biotinidase activity.
Quality of life assessments in dermatology.
  • A. Finlay
  • Medicine, Psychology
    Seminars in cutaneous medicine and surgery
  • 1998
The effectiveness of acne treatment: an assessment by patients of the outcome of therapy
It was showed that disability caused by acne can be largely reversed by effective treatment and that patient‐assessed measures of outcome can respond to changes over time and discriminate between treatments differing in effectiveness.