Isotopic study of the effects of platelets on development of intimal thickening in autologous vein grafts in dogs.

The effects of platelets on the development of intimal thickening of arterially transplanted autologous vein grafts was investigated using canine poor run-off models. A new apparatus consisting of a shielding lead block to measure in vivo platelet adherence only on the intima of the vein graft was developed. In 23 dogs, 51Cr-labelled platelets (20 microCi… CONTINUE READING