Isotope dilution gas chromatography/mass spectrometry for the determination of nickel in biological materials.

Precise and accurate methods are required to measure nickel in urine and serum samples to identify clinical states of either deficiency or toxicity. This paper presents an isotope dilution gas chromatography/mass spectrometry method for the measurement of nickel in biological samples. The method involves the preparation of a thermally stable and volatile… CONTINUE READING