Isothermal titration calorimetry of membrane proteins - progress and challenges.

Abstract

Integral membrane proteins, including G protein-coupled receptors (GPCR) and ion channels, mediate diverse biological functions that are crucial to all aspects of life. The knowledge of the molecular mechanisms, and in particular, the thermodynamic basis of the binding interactions of the extracellular ligands and intracellular effector proteins is… (More)
DOI: 10.1016/j.bbamem.2013.05.023

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Cite this paper

@article{Rajarathnam2014IsothermalTC, title={Isothermal titration calorimetry of membrane proteins - progress and challenges.}, author={Krishna Rajarathnam and Joerg Roesgen}, journal={Biochimica et biophysica acta}, year={2014}, volume={1838 1 Pt A}, pages={69-77} }