Isothermal detection of RNA with restriction endonucleases.

  title={Isothermal detection of RNA with restriction endonucleases.},
  author={Lei Yan and Shizuka Nakayama and Saron Yitbarek and Isabel Greenfield and Herman O Sintim},
  journal={Chemical communications},
  volume={47 1},
Herein, we demonstrate how to detect nucleic acids that do not contain restriction endonuclease recognition sites with restriction endonucleases. We show that the topology of DNA probes used in this detection strategy remarkably affects the efficiency of RNA/DNA detection. 

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