Isoproterenol facilitates GABAergic autapses in fast-spiking cells of rat insular cortex.

@article{Suga2014IsoproterenolFG,
  title={Isoproterenol facilitates GABAergic autapses in fast-spiking cells of rat insular cortex.},
  author={Kurando Suga},
  journal={Journal of oral science},
  year={2014},
  volume={56 1},
  pages={41-7}
}
In the cerebral cortex, fast-spiking (FS) cells are the principal GABAergic interneurons and potently suppress neural activity in targeting neurons. Some FS neurons make synaptic contacts with themselves. Such synapses are called autapses and contribute to self-inhibition of FS neural activity. β-Adrenoceptors have a crucial role in regulating GABAergic synaptic inputs from FS cells to pyramidal (Pyr) cells; however, the β-adrenergic functions on FS autapses are unknown. To determine how the… CONTINUE READING